T-Helper cell (set of 2 vials)
2 x Single Testing Vial - 10 x 50mm
T cells are also known as T lymphocytes. The “T” stands for “thymus”, the organ in which these cells mature .They are a type of white blood cell that is of key importance to the immune system and is at the core of adaptive immunity, the system that tailors the body’s immune response to specific pathogens. The T cells are like soldiers who search out and destroy the targeted invaders. T cells can produce substances called cytokines such as the interleukins which further stimulate the immune response.
T helper (Th) cells provide helper functions to other cells of the immune system—especially the antigen-presenting cells (APCs) such as macrophages, dendritic cells, and B cells—and are important for their activation and maturation.
TH1 / T Helper 1 Cell Response
Th1 cells play important roles in the identification and eradication of intracellular pathogens such as viruses and bacteria, including Mycobacterium tuberculosis, Mycobacterium leprae, and Leishmania. These pathogens typically reside in phagocytic vesicles within cells such as macrophages and often evade intracellular killing by preventing lysosomal fusion. Th1 cells help to activate macrophages against these pathogens and overcome these microbial evasion strategies. In contrast, Th2 cells, which are the other major subset of CD4+ T cells, help to recognize extracellular pathogens such as helminths and parasites and activate B cell–mediated antibody responses.
TH2 / T Helper 2 Cell Response
Th2 cells mediate the activation and maintenance of the humoral, or antibody-mediated, immune response against extracellular parasites, bacteria, allergens, and toxins. Th2 cells mediate these functions by producing various cytokines.
Note thes vials are 10 x 50mm and only fit more recent 30 vial and 75 vial flat tray foam inlay boxes:
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